3 edition of Catalog of chromosome aberrations in cancer found in the catalog.
Catalog of chromosome aberrations in cancer
Includes bibliographical references (v. 2, p. 1769-1987).
|LC Classifications||RC268.4 .M57 1991|
|The Physical Object|
|Pagination||2 v. (xxxiv, 1987 p.) ;|
|Number of Pages||1987|
|LC Control Number||90013161|
References 1. Sandberg AA. The Chromosomes in Human Cancer and Leukemia. 2nd ed. New York, NY: Elsevier Science Publishing Co. Inc; 2. Nowell PC, Hungerford D. A minute chromosome in human chronic granulocytic leukemias. Science ; 3. Mitelman F, Johansson B, Mertens F. Catalog of Chromosome Aberrations in Cancer 98' [book on CD Author: Adriana Zámečníkova. Mitelman F () Catalog of chromosome aberrations in cancer, 4th edn. Wiley-Liss, New York Google Scholar Mitelman F, Heim S () Consistent involvement of only 71 of the chromosomal bands of the human genome in primary neoplasia-associated : N. Mandahl.
Prime examples of inevitably lethal aberrations: Ring chromosome Dicentric chromosomes Anaphase bridge (chromatid aberration) Prime examples of chromosomal aberrations, potentially non-lethal: Symmetric translocations; Small deletions Note that all of these radiation-induced aberrations require two double-stranded DNA breaks. Cancer confined to the organ of origin is stage 1, cancer is locally invasive is stage 2, cancer that has spread to regional structures, such as lymph nodes, is stage 3, and cancer that has spread to distant sites, such as a liver cancer spreading to the lung or .
Chromosome Aberrations Subject Areas on Research. chromosome aberration: any deviation from the normal number or morphology of chromosomes; also the phenotypic consequences thereof.
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Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (K), or click on a page image below to browse page by page.
Links to PubMed are also available for Selected : Frederick Hecht. Full text Full text is available as a scanned copy of the original print version.
Get a printable copy (PDF file) of the complete article (K), or click on a page image below to browse page by : Lorna M Secker-Walker. For personal accounts OR managers of institutional accounts.
Username *. Password *Author: D G Harnden. Felix Mitelman is the author of Catalog Of Chromosome Aberrations In Cancer ( avg rating, 0 ratings, 0 reviews, published ), Iscn Guidelines for C /5(3).
his Catalog of Chromosome Aberrations in Cancer since before its ﬁrst publi-cation inand quite a list it has become, now including more than cases reported in more than references. In fact, the latest edi-tion is no longer just a catalog but rather a searchable database.
Instead of the 3 heavy volumes that it would. It is difficult to do justice to the scale of achievement that this book represents.
Here, in a single volume, are the phenotypes associated with the great majority of cytogenetically visible unbalanced chromosome abnormalities. At the turn of the century, this volume contains much of the information gathered since the modern era of chromosomal pathology began with Cited by: 1.
Research on DNA and chromosome aberrations focuses on cancer genetics and epigenetics. Topics include regulation of gene expression; DNA damage from exposure to chemical, physical, and endogenous agents; mechanisms of DNA damage signaling and DNA repair; and genomic instability and related molecular, cytogenetic, and chromosomal effects during tumor formation.
DNA and Chromosome Aberrations Branch. This branch administers extramural grants for studies in cancer genetics and epigenetics, including regulation of gene expression, mechanisms of DNA damage/repair, genomic instability, and related molecular, cytogenetic, and chromosomal effects during induction and progression to malignancy.
Numerical disorders. This is called aneuploidy (an abnormal number of chromosomes), and occurs when an individual either is missing a chromosome from a pair (monosomy) or has more than two chromosomes of a pair (trisomy, tetrasomy, etc.).
An example of trisomy in humans is Down syndrome, which is a developmental disorder caused by an extra copy of chromosome. Add your e-mail address to receive free newsletters from SCIRP. UC Berkeley researchers Terry Speed, Elizabeth Purdom, John Ngai and Yoon Gi Choi have joined colleagues at Berkeley Lab and around the country in creating the first comprehensive catalog of the genetic aberrations responsible for an aggressive type of ovarian cancer that causes most ovarian cancer deaths.
This “atlas” could lead to targeted treatment based on a. This text presents a comprehensive and updated catalogue of the already large, and rapidly growing number of chromosome aberrations in man. The consistent structure of the text and references provide for rapid orientation.
The catalogue should prove useful for any clinician treating patients with autosomal chromosome aberrations as well as for physicians and 5/5(2). Download PDF: Sorry, we are unable to provide the full text but you may find it at the following location(s): g (external link)Author: Frederick Hecht.
Catalog of Chromosome Aberrations in Cancer By Lorna M Secker-Walker Get PDF (0 MB)Author: Lorna M Secker-Walker. Moreover, chromosome aberrations, regardless of whether they have been molecularly characterized or not, have been shown to constitute tumor markers of.
Characterization of chromosomal aberrations in lung cancer cell lines by cross-species color banding. Catalog of chromosome aberrations in cancer, 4th edition, in two parts. Book. , human chromosome 1 contains a DNA molecule of cm length which in interphase is packed in a ﬁbrillar structure of m.
In metaphase, chromo-some 1 is about 10 m long. These packaging prob-lems are mainly solved by proteins of various types [20,21]. Due to their enormous dimensions, DNA molecules in chromosomes are permanent targets of.
Chromosome aberrations are departures from the normal set of chromosomes either for an individual or from a species. They can refer to changes in the number of sets of chromosomes (ploidy), changes in the number of individual chromosomes (somy), or changes in appearance of individual chromosomes through mutation-induced rearrangements.Catalog of Chromosome Aberrations in Cancer (4th edn) by Felix Mitelman Wiley-Liss, $ (xxxiv + pages; 2 vols) ISBN 0 1 The latest edition of the Chromosome Aberrations Catalogue is an enormous work, comprising over 14 different cases.
Even with this vast amount of.Since cancer cells often display multipolar divisions, Boveri concluded that the resulting deviant chromosome numbers were the cause of cancerous growth. Boveri’s book Zur Frage der Entstehung maligner Tumoren (“On the problem of the origin of malignant tumors”) appeared in (Wolf, ).
However, Boveri had put the cart before the by: 1.